From raw sequence to reviewable evidence

One Connected Path for
Mitochondrial DNA

GeneFlow gives principal investigators, molecular labs, and population-genetics teams one traceable workspace for sequence QC, reference-aware analysis, haplogroup review, phylogeny, and reporting.

Keep Every Result Connected to Its Evidence

Move a study forward without losing the link between source data, computational output, researcher decisions, and the report your team shares.

From Source File to Defensible Result

Carry samples from AB1, FASTA, FASTQ, or VCF through QC, haplogroup evidence, phylogenetic context, and reports without breaking the analytical record across tools.

Source Data Stays Attributable

Organize supported sequence files by project and retain checksums, upload identity, and processing status so every sample starts with a traceable source.

Govern the Work by Project

Give owners, admins, members, and viewers the access their role requires while files, samples, runs, results, and reports remain in one study context.

Automation Surfaces Evidence, Experts Interpret It

GeneFlow computes QC summaries, classifications, and trees. Researchers inspect traces, confidence, mutations, and conflicts, then document the interpretation that belongs in the scientific record.

One Workflow, Fewer Analytical Handoffs

Preserve context from the first upload to the result your collaborators review.

1. Establish the Evidence Base

Add AB1 traces, FASTA, FASTQ, or VCF to a governed project. GeneFlow tracks the source and prepares supported sample data for analysis.

2. Qualify and Analyze

Inspect chromatograms, use automated Phred flags and trim suggestions, record rCRS or RSRS as the pipeline reference, and run QC and haplogroup steps.

3. Interpret and Communicate

Review haplogroup evidence, document expert resolutions, place project sequences in a MAFFT/FastTree phylogeny, and generate sample or project reports.

Built for Teams That Need the Analysis to Hold Up

GeneFlow gives every contributor the same project context while keeping automated output distinct from scientific judgment.

Principal Investigators

Standardize how a group moves from source data to reviewed output, preserve methods across students and projects, and see where expert decisions entered the record.

Molecular & Core Labs

Receive supported sequence formats in one project, focus chromatogram review with transparent QC signals, and return reports that remain attributable to their evidence.

Population Genetics Teams

Review haplogroup evidence across samples, curate comparable consensus sequences, and build project phylogenies without detaching results from cohort provenance.

Built Around the Decisions mtDNA Teams Make

Standardize computational work while keeping scientific judgment visible.

Focus AB1 Review

Use Phred summaries, low-quality regions, four-channel traces, and suggested trim coordinates to direct attention without replacing chromatogram review.

Protect Sequence Context

Keep each consensus sequence beside its source file, sample record, AB1 evidence, and analysis history instead of passing detached sequences between tools.

Review Haplogroup Evidence

Inspect HaploGrep3 confidence and mutations, compare a recorded MitoMaster call when available, and preserve expert notes when evidence conflicts.

See Cohort Structure

Align project sequences with MAFFT, infer a FastTree phylogeny, and inspect the Newick result with its tip labels and sequence count.

Report Reviewable Findings

Generate sample or project reports that carry QC and haplogroup evidence into structured, downloadable outputs for collaborators.

Make Runs Reproducible

Define ordered or branching QC and haplogroup steps, retain their inputs and outputs, and track each run and failure in project context.

AB1 → Report

Connected Evidence Trail

rCRS / RSRS

Explicit Reference Context

MAFFT + FastTree

Established Phylogeny Methods

Role-Based

Project Access